Zulfiqar Rana, MD, MPH, FACP

Board Certified in Internal Medicine

COVID 19 Treaments

This article is for providers

Table of Contents:

Guidelines

Available Treatments

Algorithms

Resources

References

 

Guidelines:

 

Available Treatments:

Viral specific

    • Chloroquine (or hydroxychloroquine) has been reported to have some efficacy in vivo and in COVID-19 pneumonia, the mechanism may be by interfering with cellular acidification in the phagolysosome.
    • Remdesivir (Gilead; used to treat Ebola)
      • Currently, understudy in a trial in Wuhan; activity is seen in vitro with SARS-2-CoV
    • ASC09/oseltamivir, ritonavir/oseltamivir, oseltamivir
    • ASC09/ritonavir, lopinavir/ritonavir, with or without umifenovir
    • Azvudine
    • Baloxavir marboxil/favipiravir and lopinavir/ritonavir in combination(s)
    • Camostat mesylate
    • Darunavir/cobicistat alone or with lopinavir/ritonavir and thymosin α1 in combination(s)
    • Interferon alfa-2b alone or in combination with lopinavir/ritonavir and ribavirin
    • Methylprednisolone
    • Camrelizumab and thymosin
    • Tocilizumab

Management of pneumonia

Management of ARDS/ sepsis

 

Algorithms:

Algorithms are based on the following steps:

Diagnosis > Risk Stratification > Treatment

 

Resources:

Johns Hopkins Antibiotic Guide

 

References:

 

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