Simple steps to work up hypercalcemia:
- If PTHi high then follow work up for Hyperpaprathyroidism
- If PTHi normal then order
24 hour urine calcium and creatinine (Fractional excretion of Calcium)
PTHrP
TSH
SPEP, UPEP, Serum light chains
25-hydroxy Vitamin D
1,25 hydroxy Vitamin D (consider lymphoma, sarcoid, TB) - Other rare cause
Vitamin A
Thyroid
